TEMPOL, SOD mimetic

Product Details

Formal Name: 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl

Alternate Names: 4-Hydroxy TEMPO

Molecular Formula: C₉H₁₈NO₂

Formula Weight: 172.24

CAS Number: 2226-96-2

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (25 mg/ml) or in Ethanol (17 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

SOD mimetic

Functions

TEMPOL (2226-96-2) is a superoxide dismutase (SOD) mimetic. Displays protective effects in CNS kidney and radiation damage. Inhibits superoxide anion-induced inflammatory pain in mice. Blunts diabetes-induced upregulation of NADPH oxidase and ER stress in a rat model of diabetic nephropathy. Cell permeable.

Application Procedures

First dissolved in DMSO (25 mg/ml) or in ethanol (17 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)