Collection: Thermal Cyclers & PCR Instruments

It applies a controlled temperature differential across the block, so one run tests a series of annealing temperatures side by side — the fastest way to optimize a new primer pair. Benchmark's TC 9639, for example, spans a 1–30 °C differential across the block.

The lid keeps the air above the reaction hotter than the liquid, so evaporating water condenses back into the mix rather than onto the tube cap. Without it, small-volume reactions lose water, concentrations shift, and yields drop — the problem labs once solved with mineral-oil overlays.

Block format and flexibility (96- or 384-well; tubes, strips, and plates), maximum ramp rate, temperature accuracy and uniformity (the ±0.2 °C class), gradient capability, and program memory. High-throughput or regulated settings should also weigh lid-pressure consistency, connectivity, and run logging.

Instead of heating and cooling a Peltier block, systems like LGC Biosearch's Hydrocycler2 move sealed plates between temperature-controlled water baths, eliminating ramp time entirely — cycling runs roughly 40% faster. The approach suits ultra-high-throughput genotyping far more than routine benchtop PCR.

Benchmark Scientific and LGC Biosearch PCR instruments reach Israeli labs through Danyel Biotech, the official Israeli distributor of both brands. Our team matches block format and throughput to your protocols, and provides fast quotes with local service.