Sensor Chip C1

Biacore sensor chip with carboxymethylated, matrix-free surface for covalent immobilization. Use when there is a need to avoid dextran on the surface.

• Use when the interaction partner in solution is multivalent or very large.
• Maintains sensitivity by keeping large particles as close as possible to the surface.
• Reduces avidity effects with multivalent interaction partners.
• Attach proteins, nucleic acids, carbohydrates or small molecules.
• Couple to carboxyl groups on the sensor surface via -NH2, -SH, -CHO, -OH or -COOH.

Features

The matrix-free surface of Sensor Chip C1 is carboxymethylated and has a low binding capacity. The flat surface allows interactions to take place closer to the surface. These features can be beneficial when working with multivalent interaction partners, large molecules, molecular complexes and particles. This surface is also useful for those few interactions that may be affected by the presence of dextran.

Sensor chip formats for Biacore systems

Biacore sensor chips are available in two formats.

“S series” sensor chips are for use with Biacore 8K+, Biacore 8K, Biacore S200, Biacore T200, and Biacore 4000 SPR systems.

Sensor chips not designated with “S series” are designed for Biacore X100 and Biacore C SPR systems.

Documents

• Instructions for use (PDF)