pDON-AI-2 DNA

pDON-AI-2 DNA enables production of a retrovirus vector with high transfer efficiency. By transfecting the vector into an appropriate packaging cell line, the vector expresses transient or stable transcribed product containing virus-packaging signal (Ψ) and target gene. This vector possesses LTR and Ψ (viral packaging signal), but not the structural gene necessary for particle formation and replication, which are gag, pol, and env, and contains HCMV IE promoter within the U3 region of 5'LTR. The production of 2–8-fold higher-titer virus can be achieved by transfecting a version of pDON-AI-2 DNA containing a target gene compared using conventional retrovirus vector.

Features

• Retroviral vectors designed for high retroviral titers and high expression of your transgene
• Compatible with all Takara Bio brand retroviral packaging cell lines
• Vector information is listed on our vector information pages
• Fluorescent protein, MSCV, and tetracycline-inducible retroviral vectors are described elsewhere

Documents

• Safety Data Sheet (PDF)
• User Manual (PDF)
• pDON-AI-2 Neo Vector sequence file in GenBank format

Required Products

⚠️ A Required Product (e.g. an index kit) must be purchased to use this product — order one for each unit you buy.