ENAscreen Alegria Monotest

ENAscreen is an ELISA-based screening test for the qualitative determination of IgG antibodies against components of the cell nucleus in human serum or plasma.

Besides DNA and histones, autoantibodies may also target other nuclear antigens. These nuclear antigens were named extractable nuclear antigens (ENA), as originally they were extracted from the nuclei with saline solution. Autoantibodies to Smith antigen (Sm) which is also considered to be highly specific for SLE were the first anti-ENA detected. Thereafter, further subtypes of ENA i.e. ribonucleoproteins (RNP), the Sjoegren antigens SS-A and SS-B, Scl-70, and Jo-1 were identified.

Each individual well of the ENAscreen test is coated with a mixture of six highly purified antigens. For further differentiation, a positive result with this ELISA may then be followed up with ENAcombi or the ORGENTEC test kits for quantitative determination of the individual ENA specificities.

Format: Alegria® Monotest strips for the fully automated Alegria® / Alegria® 2 analyzers.

Specifications

Also available as Alegria Monotest (ORG 200, ORG 213, ORG 238, ORG 211, ORG 212, ORG 210, ORG 208, ORG 252, ORG 260, ORG 209); ELISA Kit (ORG 506, ORG 513, ORG 514, ORG 538, ORG 539, ORG 600, ORG 511, ORG 512, ORG 510, ORG 508, ORG 652, ORG 660, ORG 509).

Documents

• Instruction for Use
• Safety Data Sheet

Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.

Ordering Information