Anti-Tissue-Transglutaminase Alegria Monotest

The Anti- Tissue-Transglutaminase ELISA tests from ORGENTEC are used for automated quantitative determination of IgA and/or IgG antibodies against Tissue-Transglutaminase (tTG) in human serum or plasma. The assays Anti-Tissue-Transglutaminase IgA, Anti-Tissue-Transglutaminase IgG, and Anti-Tissue-Transglutaminase Screen support a diagnosis of celiac disease.

Celiac disease (sprue) is one of the most common food-induced diseases. It manifests itself as hypersensitivity to gluten in food, which is found in wheat, rye, and barley.

tTG belongs to a family of calcium-dependent enzymes that catalyze the transfer of protein-bound glutamine residues to primary amines. The enzyme is released by inflamed cells and is the primary antigen for autoantibodies of celiac disease patients.

The Anti-Tissue-Transglutaminase assay provides a simple, non-invasive alternative to conventional immunofluorescence. Its high reliability, sensitivity, and specificity make it an ideal tool for screening patients with clinical symptoms. The Anti-tTG test by ORGENTEC is available both for screening by simultaneous detection of IgG and IgA or as single tests for individual analysis of IgA or IgG antibodies.

Anti-Tissue-Transglutaminase IgA (Cat. no. ORG 240A-24)

Anti-Tissue-Transglutaminase IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Anti-Tissue-Transglutaminase IgG (Cat. no. ORG 240G-24)

Anti-Tissue-Transglutaminase IgG is an ELISA test for the quantitative determination of IgG antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Anti-Tissue-Transglutaminase Screen (Cat. no. ORG 240S-24)

Anti-Tissue-Transglutaminase Screen is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG and IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Format: Alegria® Monotest strips for the fully automated Alegria® / Alegria® 2 analyzers.

Specifications

Also available as ELISA Kit (ORG 540A, ORG 540G, ORG 540S).

Documents

• Instruction for Use – ORG 240A-24
• Safety Data Sheet – ORG 240A-24
• Instruction for Use – ORG 240G-24
• Safety Data Sheet – ORG 240G-24
• Instruction for Use – ORG 240S-24
• Safety Data Sheet – ORG 240S-24

Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

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