Anti-Jo-1 Alegria Monotest

Anti-Jo-1 is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against Jo-1 in human serum or plasma.

Autoantibodies against the Jo-1 antigen (histidyl-tRNA synthetase), which is one of the extractable nuclear antigens (ENA), are an accepted, highly specific marker for idiopathic myositis.

The diagnostic sensitivity of Anti-Jo-1 detection for idiopathic myositis in adults is as high 30 %, for polymyositis it is up to 46 %. In cases of juvenile myositis, on the other hand, antibodies against Jo-1 are rare. Their diagnostic specificity for autoimmune myositis is nearly 100 %. Anti-Jo-1 antibodies are absent in cases of neuromuscular disease without myositis.

Format: Alegria® Monotest strips for the fully automated Alegria® / Alegria® 2 analyzers.

Specifications

Also available as Alegria Monotest (ORG 200, ORG 206, ORG 238); ELISA Kit (ORG 506, ORG 513, ORG 514, ORG 538, ORG 539, ORG 600).

Documents

• Instruction for Use
• Safety Data Sheet

Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.

Ordering Information