Anti-beta-2-Glycoprotein Alegria Monotest

The assay contributes to the diagnosis of antiphospholipid syndrome (APS).

The clinical symptoms of APS alone are not sufficiently specific to make a definitive diagnosis. Laboratory tests thus play an important role in the diagnosis of the disease. In patients with APS, autoantibodies are formed that bind to phospholipids like cardiolipin or to phospholipid-binding proteins like beta-2-glycoprotein. Detection of these autoantibodies is an integral part of the classification criteria issued by the International Society on Thrombosis and Hemostasis.

Beta-2-GPI antibodies are associated with the occurrence of arterial or venous thrombosis, as well as with recurring miscarriage. Beta-2-GPI antibodies are considered to have a higher specificity than cardiolipin antibodies for the detection of APS; they can be detected even when the cardiolipin test result is negative.

Anti-beta-2-Glycoprotein I IgA (Cat. no. ORG 221A-24)

Anti-beta-2-Glycoprotein I IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against beta-2-glycoprotein I in human serum or plasma.

Anti-beta-2-Glycoprotein I IgG (Cat. no. ORG 221G-24)

Anti-beta-2-Glycoprotein I IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against beta-2-glycoprotein I in human serum or plasma.

Anti-beta-2-Glycoprotein I IgM (Cat. no. ORG 221M-24)

Anti-beta-2-Glycoprotein I IgM is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against beta-2-glycoprotein I in human serum or plasma.

Anti-beta-2-Glycoprotein I Screen (Cat. no. ORG 221S-24)

Anti-beta-2-Glycoprotein I Screen is an ELISA-based, automated, in-vitro test system for the quantitative determination of antibodies against beta-2-glycoprotein I in human serum or plasma. This test simultaneously tests for IgA, IgM, and IgG antibodies.

Format: Alegria® Monotest strips for the fully automated Alegria® / Alegria® 2 analyzers.

Specifications

Also available as ELISA Kit (ORG 521).

Documents

• Instruction for Use – ORG 221A-24
• Safety Data Sheet – ORG 221A-24
• Instruction for Use – ORG 221G-24
• Safety Data Sheet – ORG 221G-24
• Instruction for Use – ORG 221M-24
• Safety Data Sheet – ORG 221M-24
• Instruction for Use – ORG 221S-24
• Safety Data Sheet – ORG 221S-24

Instruction for Use Revision 7. Earlier versions and additional languages can be found in the document archive.

Ordering Information