LambdaFabSelect

LambdaFabSelect is an affinity resin designed for the purification of human lambda Fab fragments, with high binding capacity, purity, and yield.

• Rigid agarose base matrix allows high flow rates and processing of large sample volumes for increased throughput
• Non-mammalian derived product reduces regulatory concerns in the production of Fabs for clinical applications

LambdaFabSelect is an affinity resin designed for the purification of human lambda Fab fragments. The ligand binds to the constant region of the light chain enabling an efficient capture step for human antibody fragments such as Fabs with high purity and yield.

Antibody fragments, especially Fabs, are getting increased attention as potential biopharmaceuticals because they have some advantages over monoclonal antibodies (Mabs). For example, Fabs show improved pharmacokinetics for tissue penetration and can bind to targets inaccessible to conventional antigen-binding sites.

The product is a part of Cytiva's Custom Designed resins program.

Documents

• Data file (PDF)