With a high binding capacity and small bead size, Capto™ SP ImpRes strong cation exchanger is a good choice for reliable and robust polishing steps in industrial purification.
- High-resolution intermediate purification and polishing resin based on the well-established Capto™ platform with traditional ligands. Smaller particle size compared with Capto™ S.
- Flexible process design due to large operational window of flow rates and bed heights.
- High throughput purifications easy to optimize and scale-up.
- Higher manufacturing productivity enables improved process economy.
- Resin fulfills industrial demands for security of supply, robust performance, and regulatory support
Designed for large feed volumes
Capto™ SP ImpRes is a strong cation exchanger for the high-throughput intermediate purification and polishing steps of a wide range of biomolecules. This chromatography resin is part of an expanded high-resolution platform based on the high-flow agarose Capto™ product line.
By combining the high-flow characteristics of Capto™ resin with a small particle size, Capto™ SP ImpRes delivers excellent pressure-flow properties with impressive resolution. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.
Suits large-scale purification processes
Capto™ SP ImpRes is a BioProcess™ chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto™ base matrix and with traditional ionic group ligands, it provides many opportunities for improved productivity and straightforward process development.
Prepacked columns and other formats
Capto™ SP ImpRes resin is available in the following formats:
Process development scale: prepacked
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PreDictor™ filter plates, 96-well plates for high-throughput screening or process development.
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PreDictor™ RoboColumn™ units, miniaturized columns for high-throughput process development.
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HiScreen™ columns, optimized for method and process development.
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Validation columns, scale-down columns for robust and reproducible process validation and process development (Tricorn™ format)
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f(x) columns, precalibrated chromatography column for fast and accurate mechanistic modeling during downstream process development.
Lab scale: prepacked for manual purification
HiTrap™ columns, for easy use with a syringe, peristaltic pump, or chromatography system.
Lab scale: prepacked for automated purification and analysis
HiTrap™ columns, for easy use with a syringe, peristaltic pump, or chromatography system.
Process characterization: resin kits
Process Characterization Kit, designed for studying the potential impact that resin ligand density might have on the process outcome.
Process-scale purification: prepacked
ReadyToProcess™ columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.
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