AmpliSeq for Illumina Myeloid Panel 20024478 - Illumina

AmpliSeq for Illumina Myeloid Panel

Name: AmpliSeq for Illumina Myeloid Panel
Brand: Illumina
SKU: 20024478
Availability: InStock

Vendor: Illumina

SKU: 20024478

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Fixed panel includes 74 genes associated with hematologic malignancies. Kit contains 24 reactions (24 DNA libraries and 24 RNA libraries). Requires 48 reactions of LP PLUS. Library PLUS, indexes and cDNA synthesis sold separately.

The Myeloid Panel enables concurrent analysis of both DNA and RNA from blood and bone marrow samples in a single assay to study biomarkers associated with hematologic malignancies. The panel covers relevant targets for these major myeloid disorders: acute myeloid leukemia (AML), myeloid dysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), chronic myeloid leukemia (CML), chronic myelomonocytic leukemia (CMML), and juvenile myelomonocytic leukemia (JMML). Key features include:

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Specifications

Area of interest Cancer research
Assay time 5.5 – 7.5 hours (library prep only; doesn't include library quantification, normalization, or pooling time)
Cancer type Hematologic
Content specifications Targets biomarkers across 69 genes (40 key DNA target genes, 29 RNA fusion driver genes, and 5 gene expression levels)
Hands on time < 1.5 hr
Input quantity 20 ng high-quality DNA; 10 ng high-quality RNA (10 ng recommended per pool)
Instruments MiSeq SystemMiniSeq System
Key use Targeted analysis
Method Amplicon sequencing, Targeted DNA sequencing, Targeted RNA sequencing
Multiplexing Up to 96-plex
Nucleic acid type DNA, RNA
Specialized sample types Blood, Bone marrow, Not FFPE-compatible
Species category Human
Sub category Library preparation kits
Technology Sequencing
Variant class Gene fusions, Insertions-deletions (indels), Single nucleotide polymorphisms (SNPs), Somatic variants

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