Seraseq HRD gDNA Mix High-Positive (0710-2879)

Seraseq HRD gDNA Mix Low-Positive (0710-2880)

Seraseq HRD gDNA Mix Negative (0710-2881)

Seraseq® HRD gDNA Mix

Vendor: SeraCare

SKU: 0710-2879

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Genomic instability resulting from homologous recombination DNA repair deficiency (HRD) is a response biomarker to assess ovarian and breast cancer patient eligibility for PARP inhibitor and platinum-based therapies. HRD measurements have the potential to improve cancer therapy, however standardizing and democratizing HRD measurements remains challenging due to their inherent complexity. This cell line-derived HRD reference material can support the development, validation, and routine use of assays determining HRD status in cancer patients.

FEATURES

Derived from tumor and matched-normal human cell lines

Allows blending to desired % tumor content with included SNP-matched normal cell line gDNA

20 µL of both tumor and matched normal gDNA at 25 ng/µL

Additional biosynthetic single-nucleotide variants (SNVs) of 4 homologous recombination repair (HRR) genes

HRD status validated by targeted Next Generation Sequencing (NGS)

Manufactured in GMP-compliant, ISO 13485-certified facilities

Documents

Ordering Information

Cat. no.	Product	Size
0710-2879	Seraseq® HRD gDNA High-Positive Mix	2 x 20 µL
0710-2880	Seraseq® HRD gDNA Low-Positive Mix	2 x 20 µL
0710-2881	Seraseq® HRD gDNA Negative Mix	2 x 20 µL

Specifications

Pack size 2 x 20 µL
Sub category Solid Tumors

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