Seraseq® ctDNA Extraction Reference Material

Preparation of a liquid biopsy sample starts with a blood draw from a patient followed by extraction of cfDNA from plasma. The concentration of cfDNA in a blood draw can vary greatly from patient to patient, but reference materials are typically built to a single cfDNA concertation. Additionally, extraction kits do not provide robust feedback about root cause of extractions resulting in lower than expected yield which increases the challenge of decoupling extraction kit performance from pre-analytic sample handling.

LGC Clinical Diagnostics has produced the Seraseq ctDNA Extraction Reference Materials to allow clinical labs to validate and assess performance of cfDNA extractions in a more comprehensive manner. The ctDNA Extraction Reference Materials are available at concentrations of 20, 50 and 80 ng/mL in synthetic plasma. In addition to being useful as total cfDNA extraction reference materials, the samples contain four EGFR variants present at 1% ctDNA to represent tumor ctDNA. Each kit comes with 4x single-use vials for ease of use at an affordable price point.

Documents

• Seraseq® ctDNA Extraction Reference Material 20 ng/mL Product Sheet (Product Sheet)
• Seraseq® ctDNA Extraction Reference Material 50 ng/mL Product Sheet (Product Sheet)
• Seraseq ctDNA Extraction Reference Material 80 ng/mL Product Sheet (Product Sheet)
• Seraseq® ctDNA Extraction Reference Material 20 ng/mL, 50 ng/mL, 80 ng/mL (Package Insert)
• Technical Spreadhseet for Seraseq ctDNA Extraction Reference Material (Technical Spreadsheet)
• Seraseq ctDNA Extraction Reference Material Non-Requirement Letter (SDS Non-Requirement Letter)

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