Hedera Profiling RNA Tissue Test Panel (HP RNA), 43-Gene NGS Fusion & Expression Kit, 24 Tests

Hedera Profiling RNA (HP RNA) is a 43-gene, hybrid-capture NGS panel for FFPE tissue RNA. It detects fusions with partner-agnostic discovery, gene expression, alternative splicing and actionable exon skipping, and includes all major ESCAT genes and all OncoKB Level 1, 2 and 3 genes for solid tumors. Works with as little as 30 ng of RNA; 24 tests per kit.

Kits are commercialized together with the Hedera Prime software and can be purchased separately.

Key Features

• Compact but comprehensive: 43 genes to detect fusions (partner-agnostic discovery), gene expression profiling, alternative splicing and splice variants and actionable exon skipping detection for functional insights
• Highly actionable: Includes all major ESCAT genes and all OncoKB Levels 1, 2, 3 for solid tumors
• Fast and accurate: Swiftly integrates into your routine NGS workflow to get accurate results within 5 calendar days, with as little as 30 ng of RNA
• Robust software analysis: Backed by Hedera Prime software, save time on each report while ensuring accurate and reliable results

Workflow

The kit integrates into your existing NGS workflow and sequencing instrument; tertiary analysis and reporting run in the Hedera Prime software.

• 3 hours - hands on time
• 5 calendar days - from sample to report
• < 5 minutes - tertiary analysis & reporting

Specifications

Gene List

Tumor types: Lung Cancer, Colorectal Cancer, Melanoma, Thyroid Cancer, Gastrointestinal Stromal Tumors (GIST), Cholangiocarcinoma and other solid tumors.

AKT1, ALK, AR, BRAF, BRCA1, BRCA2, CD274, CIC, CLDN18, EGFR, ERBB2, ERBB3, ERG, ESR1, ETV1, ETV6, EWSR1, FGFR1, FGFR2, FGFR2b, FGFR3, MAP2K1, MET, MYC, NRG1, NTRK1, NTRK2, NTRK3, NUTM1, PAX3, PAX8, PDGFB, PGR, PLAG1, PPARG, RAF1, RET, ROS1, SS18, STAT6, TMPRSS2, USP6

Ordering Information

For Research Use Only. Not for use in diagnostic procedures. This product is intended for laboratory research purposes only and is not intended for use in the diagnosis, prevention, monitoring, treatment, or alleviation of disease. This product has not been cleared or approved by any regulatory authority for clinical or diagnostic use.