Archer VARIANTPlex Solid Tumor Focus v2 Panel

Identify DNA profiles of multiple cancers with one focused panel

Detect single nucleotide variants, copy number variations, insertions, deletions, and microsatellite instability status with NGS for 20 genes relevant for colorectal cancer, breast cancer, melanoma, NSCLC, and other solid tumor cancer research.

Detect confidently with Archer VARIANTPlex NGS panels for DNA.

Key Benefits

• Detect confidently — A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.
• Less QNS — Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue.
• Achieve efficiency — Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
• Customize content — Use Assay Marketplace to modify any panel to fit your lab's needs or start from scratch to keep up with the pace of discovery.

Panel Specifications

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

Gene Targets

AKT1, BRAF, EGFR, ERBB2, FOXL2, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MET, NRAS, PDGFRA, PIK3CA, RET, TERT, TP53

Documents

User guides and protocols

• VARIANTPlex-HT Protocol for Illumina (PDF)
• VARIANTPlex HS-HGC Protocol for Illumina (PDF)

Product inserts

• VARIANTPlex-HT Solid Tumor Focus v2 Panel Product Insert (PDF)
• VARIANTPlex Solid Tumor Focus V2 Product Insert (PDF)

Ordering Information

HT kits are liquid reagents for high-throughput / automated workflows (Illumina only). For research use only. Not for use in diagnostic procedures.