Archer IMMUNOVerse BCR Panel

SKU: DB0240

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Assess clonalities, MRD, and more with a targeted RNA assay

Characterize B-cell clonalities, including isotypes and subclasses in the Fc region and somatic hypermutations within the variable regions, with targeted NGS of B-cell receptor chain RNA relevant for blood cancer and solid tumor research.

Key Benefits

Secure data — Assessing samples in-house means you retain important data for further studies, ensuring all your data remains user-owned.
Identify more — Anchored Multiplex PCR (AMP™) chemistry amplifies effectively through hypervariable sequences and variable length fragments enabling rare clone detection, even for potentially degraded FFPE tissue.
Clarify confidently — Archer Analysis corrects for amplification bias and sequencing errors to provide a true and reproducible measure of diversity and can be used for disease monitoring, repertoire profiling, and somatic hypermutation detection.
Achieve efficiency — Parallel workflows across all Archer panels provides streamlined genomic characterization, while single use, reaction-sized lyophilized reagents minimize hands-on time and potential pipetting errors.

Panel Specifications

Target regions	BCR heavy (IGH) and light (kappa/lambda) chains
Applications	Clonality, MRD, profiling, somatic hypermutation
Input RNA required*	20 ng to 6 μg
Recommended number of reads*	250 K to 10 M
Hands-on time	3.5 hours
Total library prep time	1.5 days
Platform compatibility	Illumina®
Reagent format	Lyophilized
Supported sample types	Blood, PBMC, bone marrow, sorted B cells, FFPE, fresh frozen tissue

*Input mass and read requirements vary depending on type, quality, B cell content, and application.

Documents

User guides and protocols

IMMUNOVerse-HS BCR Protocol for Illumina (PDF)

Ordering Information

Cat. #	Kit	Format
DB0240	IMMUNOVerse-HS CSTM BCR IGH ILMN 8rxn	IGH / Illumina / 8 rxn
DB0221	IMMUNOVerse-HS CSTM BCR IGH/K/L ILMN 8rxn	IGH/K/L / Illumina / 8 rxn
DB0241	IMMUNOVerse-HS CSTM BCR IGK/L ILMN 8rxn	IGK/L / Illumina / 8 rxn

HT kits are liquid reagents for high-throughput / automated workflows (Illumina only). For research use only. Not for use in diagnostic procedures.

Specifications

Assay time 1.5 days
Content specifications BCR heavy (IGH) and light (kappa/lambda) chains
Hands on time 3.5 hours
Input quantity 20 ng to 6 μg
Platform compatibility Illumina
Reagent type Lyophilized
Specialized sample types Blood, PBMC, bone marrow, sorted B cells, FFPE, fresh frozen tissue
Sub category IMMUNOVerse
Variant class Clonality, MRD, profiling, somatic hypermutation

links and documants

Protocol url Click here
Source url Click here