Zerumbone, Apoptosis enhancer

Product Details

Formal Name: (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one

Molecular Formula: C₁₅H₂₂O

Formula Weight: 218.34

CAS Number: 471-05-6

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (25 mg/ml) or in Ethanol (25 mg/ml).

Storage: 4°C

Stability: ≥ 2 years.

Applications

Apoptosis enhancer

Functions

Natural sesquiterpene ketone isolated from Zingiber sp. Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Induces apoptosis in T-acute lymphoblastic leukemia cells. Has no cytotoxic effect on normal cells. Cell permeable.

Application Procedures

First dissolved in DMSO (25 mg/ml) or in Ethanol (25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 2 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)