DynaPro NanoStar II Dynamic Light Scattering Instrument
Vendor: Wyatt Technology
SKU: WDN-0100
In stock
Traditional dynamic light scattering, just better.
Unique cuvette-based DLS
The DynaPro NanoStar II is a unique cuvette-based DLS instrument used for the analysis of proteins, gene therapy vectors, viruses and virus-like particles, promiscuous inhibitors, micelles, liposomes, lipid and metallic nanoparticles, and more. To accommodate scarce and precious samples, specially designed quartz cuvettes afford robust, accurate measurements with as little as 2 µL of solution, while our proprietary disposable cuvettes provide comparable sensitivity with as little as 4 µL!
Walk-up operation with DYNAMICS Touch™
The NanoStar is the only DLS instrument to provide a fully integrated, walk-up measurement experience. No need to boot up your lab PC, launch the DLS software, connect to the instrument and worry about where your data files are stored. DYNAMICS Touch is an intuitive—yet capable—DLS measurement app that resides right on the NanoStar. Via the full-size touch screen display, DYNAMICS Touch guides you through the entire setup and measurement process. It tells you if the data quality is sufficient for confidence in the results, and displays them instantly. Data files and concise PDF reports can be stored on the instrument, transferred via the network or downloaded to a flash drive. You can even send the report to your phone!
Full-featured analyses with DYNAMICS™
DYNAMICS is our powerful PC-based, comprehensive software package for collecting, analyzing, and reporting batch dynamic and static light scattering data. It performs advanced analyses and compares multiple data files to identify trends and statistics. DYNAMICS can control the NanoStar and acquire data directly, or read in DYNAMICS Touch data files.DYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the DynaPro NanoStar in a GMP environment for quality control or at-line process monitoring.
Size and beyond
Coupled with the versatile and user-friendly DYNAMICS™ software and DYNAMICS Touch™ on-board app, the NanoStar may be utilized to measure not just size, size distributions, particle concentration and weight-average molar mass, but also solution properties relevant to sample stability: the second virial coefficient (A2 or B22), the diffusion interaction parameter (kD), turbidity or opalescence and the temperature of protein melting or aggregation onset (Tm, Tonset).
Cuvette, and yet...
... still another feature unique to the NanoStar: the optical fiber pickup may be coupled to any of Wyatt's on-line MALS detectors - the DAWN™ or miniDAWN™ - to add on-line DLS measurements in the same detection volume as SEC-MALS or FFF-MALS measurements.
Combining numerous benefits, the NanoStar is an unparalleled cuvette-based DLS detector. For higher productivity, consider the DynaPro™™ Plate Reader, the only commercially available DLS plate reader measuring in situ for high-throughput screening of thousands of conditions per day in industry-standard microwell plates.
Key features
- DYNAMICS Touch on-board app for walk-up operation
- Rh from 0.2 nm - 1000 nm
- Temperature from -10 °C to +120 °C
- Molecular weight from 300 Da to 1 MDa
- Turbidity from 1 to 80 NTU
- Separate, optimized SLS and DLS detection channels
- Auto-attenuation over five orders of magnitude
Versatile, high-quality options
Make measurements in super-high-quality quartz cuvettes with as little as 2 µL of sample, aqueous or organic solvents, over the entire, extended temperature range. This cuvette incorporates a solvent reservoir to prevent sample evaporation over high-temperature or extended analyses.
Our proprietary disposable cuvettes nearly match the optical quality of quartz yet require only 4 µL of sample, aqueous or select polar solvents. For convenience, larger-volume quartz and disposable cuvettes are also available.
Click to enlarge.
Specifications
| Size Range (Radius) | 0.2 to 1000 nm |
| Static Scattering Molecular Weight Range | 300 Da to 10 MDa |
| Turbidity Range | 1 to 80 NTU |
| Particle Concentration Range | 1x10 to 1x 10 (dependent on size) |
| Sensitivity | 0.1 mg/mL of 14.4 kDa lysozyme in PBS |
| Temperature Range | -10 °C to +120 °C Maximum ramp rate 15 °C/min |
| Sample Cells | Quartz cuvette: 2 μL or 45 μL, Disposable cuvette (cyclic olefin copolymer), generic 4 mL quartz and disposable cuvettes (with adapter) |
| Minimum Sample Volume | 2 μL in quartz cuvette; 4 μL in disposable cuvette |
| Laser Wavelength | 658 nm |
| Laser Power Control | Programmable 10% to 100% |
| Scattering Angle | 90° |
| Optical Fiber | Multi-mode |
| Additional Detectors | Laser monitor for active stabilization; Forward monitor measures transmitted light for turbidance and laser/cell diagnostics |
| Data Acquisition Time | 1 to 3600 sec |
| Correlator | 512 channel, 100 nsec sampling time in a multi-tau layout |
| Dimensions | 57 cm (L) x 36 cm (W) x 20 cm (H) |
| Weight | TBD |
Documents
Specifications
- Dimensions 57 cm (L) x 36 cm (W) x 20 cm (H)
- Instrument family DynaPro NanoStar
- Laser wavelength 658 nm
- Molecular size range 0.2 to 1000 nm
- Sensitivity 0.1 mg/mL of 14.4 kDa lysozyme in PBS
- Software DYNAMICS 8 (standard, with DYNAMICS Touch, or with Security Pack)
- Sub category Dynamic & Electrophoretic Light Scattering
- Temperature range -10 °C to +120 °C Maximum ramp rate 15 °C/min
links and documants
- Brochure url Click here
- Source url Click here
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DynaPro NanoStar II Dynamic Light Scattering Instrument
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