TruSight Oncology 500 ctDNA v2 for Use with NovaSeq 6000 S4 Flow Cell (24 samples) 20105902 - Illumina

TruSight Oncology 500 ctDNA v2 Automation Kit plus Illumina Connected Insights Software, for Use with NovaSeq 6000 S4 Flow Cell (48 samples)

Name: TruSight Oncology 500 ctDNA v2 Automation Kit plus Illumina Connected Insights Software, for Use with NovaSeq 6000 S4 Flow Cell (48 samples)
Brand: Illumina
SKU: 20105916
Price: 64507.00 ILS
Availability: InStock

Vendor: Illumina

SKU: 20105916

64,507.00 NIS

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Mixed Workflow TSO 500 ctDNA v2 + S4 FC Automated Kit+ Illumina Connected Insights Software

TruSight Oncology 500 ctDNA v2 is a pan-cancer NGS assay that enables in-house comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) in blood plasma for research.

Documents

Support Documentation

Specifications

Area of interest Cancer research, Cell & molecular biology research, Drug discovery & development, Immuno-oncology research
Assay time 2.5–4 days from purified nucleic acid to variant results
Automation capability Liquid handling robot(s)
Cancer type Pan-cancer, Solid tumor
Content specifications Targeted sequencing of DNA for a total of 1.94 Mb panel size: 523 genes for small variants, 59 genes for CNVs, 23 genes for gene rearrangements, bMSI (> 2300 loci), bTMB (1.94 Mb).
Hands on time ~1.5 hr for automated workflow ~2.5 hr for manual workflow
Input quantity 20 ng cfDNA (4 ml of plasma)
Instruments NextSeq 2000 SystemNovaSeq 6000 SystemNovaSeq 6000Dx in Research ModeNovaSeq X Plus SystemNovaSeq X System
Key use Genotyping, Targeted analysis, Tumor immunogenicity analysis
Mechanism of action Hybrid-capture chemistry
Method Target enrichment, Targeted DNA sequencing
Multiplexing NextSeq 2000 System: 4 samples on P4 flow cell. NovaSeq 6000 System: 4 samples on S1 flow cell, 8 samples on S2 flow cell, 24 samples on S4 flow cell. NovaSeq X Series: 4 samples on 1.5B flow cell, 24 samples on 10B flow cell, 64 samples on 25B flow cell.
Nucleic acid type DNA
Specialized sample types Blood, Circulating tumor DNA
Species category Human
Technology Sequencing
Variant class Blood microsatellite instability (bMSI), Blood tumor mutational burden (bTMB), Copy number variants (CNVs), Gene rearrangements, Insertions-deletions (indels), Multi-nucleotide variants (MNVs), Single nucleotide variants (SNVs)

links and documants

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