Trolox, Antioxidant, water soluble

Product Details

Formal Name: 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

Molecular Formula: C₁₄H₁₈O₄

Formula Weight: 250.30

CAS Number: 53188-07-1

Purity: ≥98%

Formulation: Powder.

Solubility: Soluble in DMSO (25 mg/ml); or ethanol (25 mg/ml); or water at alkaline pH

Storage: Room temperature

Stability: ≥ 2 years protect from light

Applications

• Antioxidant.

Functions

Water soluble derivative of vitamin E with potent antioxidant and radical scavenging activities. Prevents lipid peroxidation induced by CYP2E1 in Hep G2 cells. Inhibits peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes. Attenuates impaired proliferation of oxidatively stressed myoblasts overexpressing parkin interacting substrate (PARIS/ZNF746). Frequently employed as a benchmark compound to compare the antioxidant capacity of other compounds and reference standard for determination of “trolox equivalents”.

Application Procedures

Trolox can be first dissolved in DMSO (25 mg/ml); or ethanol (25 mg/ml), or water at alkaline pH, then diluted to aqueous buffer. Prepare fresh solutions daily. Do not store solutions.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)