Solubility: Soluble in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Ubiquitin ligase inhibitor
Functions
TAME binds to the ubiquitin ligase anaphase-promoting complex (APC) preventing its activation by Cdc20 and Cdh1 and resulting in mitotic arrest.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
