SU-5402, FGFR Phosphorylation inhibitor

Product Details

Formal Name: 3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid

Alternate Names: PF-02969207

Molecular Formula: C₁₇H₁₆N₂O₃

Formula Weight: 296.32

CAS Number: 215543-92-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

FGFR Phosphorylation inhibitor

Functions

Inhibits FGFR phosphorylation in vitro, in cell culture, and in mouse tumor cell models. SU-5402 can suppress ECP induced cardiomyocyte differentiation of P19CL6 embryonic carcinoma cells via an FGFR3 dependent pathway.

Application Procedures

First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)