SR-9009, RevErb a/b agonist

Product Details

Formal Name: Ethyl 3-(((4-chlorobenzyl)((5-nitrophen-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate hydrochloride

Molecular Formula: C₂₀H₂₄CLN₃O₄S · HCl

Formula Weight: 474.40

CAS Number: 1379686-30-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (up to 20 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

RevErb a/b agonist

Functions

Agonist at nuclear receptor Rev-ErbA. Greatly diminishes VILI-induced lung edema, inflammatory cell infiltration and TNFα production in a rat lung injury model. Suppresses atherosclerosis in a mouse model.

Application Procedures

First dissolved in DMSO (greater than 25 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)