SOPHiA DDM™ Lymphoma Solution (LYS)

The SOPHiA DDM™ Lymphoma Solution (LYS) is a comprehensive capture-based application designed to detect and analyze genomic alterations on 54 genes associated with various B- and T-cell lymphomas.

Sample-to-report bundle: capture-based target enrichment and library preparation kit combined with the analytical capabilities of the SOPHiA DDM™ Platform.

Specifications

Key Features

Gain a complete view of Lymphoid Malignancies – Go from sample to report with SOPHiA DDM™ for Lymphoid Malignancies. Leverage our flexible platform that offers a comprehensive range of guideline-driven, ready-to-use, and customizable next-generation sequencing (NGS)-based applications to enhance your genomic profiling capabilities.

Workflow

Charting the course to solve lymphoid cases – Streamline your analysis with an accurate and adaptable workflow.

A wave of insights for every laboratory – Streamline your blood cancer analysis workflow from sample to comprehensive, customized report.

• Flexible and scalable library preparation – Rely on robust sequencing across multiple applications using one universal and automated protocol.
• Accurate variant detection and annotation – Precisely detect challenging genomic variants thanks to the power of our proprietary algorithms.
• Customizable reporting – Quickly prepare comprehensive reports tailored to your needs.

Analytics

Turning data into insights—it’s in our blood – Gain deeper insights into lymphoid malignancies by accurately assessing even the most challenging molecular biomarkers with the advanced power of SOPHiA DDM™'s proprietary algorithms.

• Sensitive SNV and Indel detection – Accurately identify single nucleotide variants (SNVs) and small insertions/deletions (Indels) in lymphoid malignancies, even in challenging samples. PEPPER™’s sophisticated algorithm differentiate true signal from noise, providing you with reliable results to guide your decisions.
• Accurate CNV calling – Gain crucial insights into the genomic alterations driving lymphoid malignancies with MUSKAT™. Our copy number variation (CNV) calling algorithm adapts to experimental conditions and performs double normalization to call CNVs missed by other tools.
• Robust variant annotation – Confidently interpret the significance of genomic variants in lymphoid malignancies with MOKA™. Our robust annotation algorithm draws from curated databases and uses de novo analytics to provide insights on the likely effects and pathogenicity of genomic variants.
• Explore IGH and IGL rearrangement – SOPHiA GENETICS worked with IDIBAPS to enable IgCaller companion software to be used with SOPHiA DDM™ Community CLL Clonality Solution.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.