Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 2 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Autophagy inducer
Functions
Induces autophagy via an mTOR-independent pathway. Enhances clearance of β-amyloid protein in cell lines and primary neuronal culture models. May be a useful lead compound for the development of new therapeutics for neurodegenerative diseases. Induces the release of articular cartilage vesicles from healthy articular chondrocytes in a dose- and time-dependent manner. Promotes reprogramming of fibroblasts to neural stem-like cells. Cell permeable..
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 2 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
