Salermide, SIRT1&2 inhibitor

Vendor: TriBioScience

SKU: TBI1514-5MG

409.00 NIS

Stock on Request

In stock

Product Details

Formal Name: N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide

Molecular Formula: C₂₆H₂₂N₂O₂

Formula Weight: 394.47

CAS Number: 1105698-15-4

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 40 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)

Storage: -20°C

Stability: ≥ 2 years.

Applications

SIRT1&2 inhibitor

Functions

Salermide (1105698-15-4) is a SIRT1 and SIRT2 inhibitor. Exhibits a stronger inhibitory effect on SIRT2 than on SIRT1 in vitro. Induces the reactivation of proapoptotic genes repressed by SIRT1 and causes massive apoptosis in cancer cells within 24 hours. Displays protective effect in nematodes expressing muscular dystrophy protein. Promotes neuronal apoptosis confirming the protective effect of SIRT1.

Research use only.

Documents

Specifications

Cas number 1105698-15-4
Formal name N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide
Formulation Powder
Formula weight 394.47
Molecular formula C26H22N2O2
Purity >98%
Solubility Soluble in DMSO (up to 40 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Stability ≥ 2 years
Storage -20°C

links and documants

Datasheet url Click here
Msds url Click here
Source url Click here