RetroNectin® Pro (Recombinant Human Fibronectin Fragment)

RetroNectin Pro is a 63-kD fragment of recombinant human fibronectin (also referred to as rFN-CH-296) that enhances the efficiency of lentiviral- and retroviral-mediated gene transduction. This is particularly important for hematopoietic cells and other hard-to-transfect cell types.

Features

• Enhanced gene transfer efficiency for retroviral or lentiviral transduction of suspension cells, hematopoietic stem cells, and other hard-to-infect cell types
• Less toxicity than other commonly used transduction enhancers, including polybrene and protamine
• Fully recombinant peptide
• The efficiency of T cell (CD8+) expansion can be significantly increased in the presence of RetroNectin reagent
• Takara Bio Inc., has submitted a Drug Master File (DMF application number 18898) to the Food and Drug Administration for RetroNectin GMP grade.

Documents

• Certificate of Analysis (PDF)
• Safety Data Sheet (PDF)