ReadyToProcess ™ chromatography columns are validated high-performance bioprocessing columns that are supplied prepacked and ready for use. These columns are prepacked with Capto ™ Core 700 chromatography resin for purification of large entities such as viruses and viral vectors.
Novel core bead technology and multimodal, octylamine ligand give Capto Core 700 dual functionality. This chromatography resin has both size exclusion and binding properties.
Novel core bead technology allows efficient capture of contaminants while target molecules are collected in the flowthrough.
Significantly improved productivity and higher flow rates compared with standard size exclusion (gel filtration) methods.
Straightforward optimization due to flowthrough chromatography and robust performance.
Convenient small-scale purification, process development, and scale-up using prepacked HiTrap and HiScreen columns.
Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
Capto Core 700 is composed of a ligand-activated core and an inactive shell. The inactive shell excludes large molecules (cut off ~ Mr 700 000) from entering the core through the pores of the shell. These larger molecules are collected in the column flowthrough, while smaller impurities bind to the internalized ligands.
