Product Details
Formal Name: 4-[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
Molecular Formula: C17H13N3O7
Formula Weight: 371.31
CAS Number: 418805-02-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
E1 UAE inhibitor
Functions
Inhibits ubiquitin activating enzyme E1 (>60% inhibition at 10 µM) with little or no activity against E2 or E3. Cell permeable
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 1 week.
Research use only.
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