Solubility: Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Translation inhibitor
Functions
Puromycin is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is a protein synthesis inhibitor that disrupts peptide transfer on ribosomes causing premature chain termination. It is an inhibitor of dipeptidyl-peptidase II and cytosolic alanyl aminopeptidase. Puromycin also inhibits protein transport in mitochondria.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
