Poly-D-Lysine is a synthetic polymer composed of D-lysine units, which are positively charged, enhancing cell attachment and adhesion to both plasticware and glass surfaces. It is particularly useful for culturing cell types that are sensitive to proteases, as these cells can degrade Poly-L-Lysine. For such applications, Poly-D-Lysine is preferred due to its resistance to enzymatic degradation. This molecule has been widely used to support the adhesion of a variety of cell types, especially neural cells.
The molecular weight of Poly-D-Lysine can vary, with lower molecular weight (around 30,000 Da) being less viscous and higher molecular weight (>300,000 Da) offering more binding sites per molecule. This product’s molecular weight ranges from 70,000 to 150,000 Da, providing a solution with optimal viscosity for ease of handling while maintaining enough binding sites to support effective cell attachment.
