PluriSln 1, Stearoyl CoA desaturase inhibitor

Product Details

Formal Name: N’-Phenylpyridine-4-carbohydrazide

Alternate Names: 4-Pyridinecarboxylic acid 2-phenylhydrazide

Molecular Formula: C₁₂H₁₁N₃O

Formula Weight: 213.24

CAS Number: 91396-88-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Stearoyl CoA desaturase inhibitor

Functions

PluriSln 1 is an inhibitor of stearoyl-coA desaturase (SCD1). PluriSln 1 was able to selectively eliminate human pluripotent stem cells (hPSCs) while not affecting a large array of progenitor and differentiated cells. The ability to eliminate potentially tumorigenic undifferentiated cells is important for increasing the safety of hPSC-based treatments. PluriSln 1 has been used to successfully eliminate tumorigenic cells in cardiomyocytes and chondrogenic cells.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 1 month.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)