The PicoPLEX Gold Single Cell DNA-Seq Kit is designed to generate high-quality DNA libraries from single cells for sequencing on Illumina platforms. The kit is based on innovative PicoPLEX technology and yields libraries with superior reproducibility from 1–5 mammalian cells or genome equivalents of gDNA as input, providing reliable results from challenging samples such as formalin-fixed single cells. Single index and unique dual index kits are available and must be purchased separately. This product is composed of four 96-reaction kits (Cat. # R300670), 384 reactions total, of PicoPLEX Gold Single Cell DNA-Seq reagents.
Features
Highly reproducible and accurate characterization of CNVs, SNVs, and other relevant genomic variants from single cells
Outperforms MDA WGA technology for CNV and SNV detection
Streamlined three-hour workflow integrates WGA and library prep with less than 30 minutes of hands-on time
Highly uniform coverage with low allele drop-in and drop-out rates
Applications
Whole genome amplification and library preparation for the following applications: Cancer research: circulating tumor cells, cells or DNA from laser capture microdissection (LCM), and cells from fine needle aspirate (FNA) Reproductive health research: embryonic cells and circulating fetal cells Deve
