PBMC, TRPM8 blocker

Product Details

Formal Name: (S)-1-Phenylethyl(2-aminoethyl)(4-(benzyloxy)-3-methoxybenzyl)carbamate

Molecular Formula: C₂₆H₃₀N₂O₄

Formula Weight: 434.54

CAS Number: 1352138-54-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

TRPM8 blocker

Functions

Potent and selective inhibitor of TRPM8 channels. PBMC inhibits both chemical and thermal activation of TRPM8. Reverses the menthol and cold-induced facilitation of the micturition reflex.Represents a new lead for analgesic drugs based on blocking TRPM8.

Application Procedures

First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)