Anti-HSV-2 Alegria Monotest

The human pathogenic type 1 and 2 herpes simplex viruses (HSV-1 and HSV-2) infect epithelial cells of the mucous membranes: HSV-1 primarily in the head area (herpes labialis), HSV-2 in the genital and anal areas (herpes genitalis). In the acute stage, the infection causes formation of characteristic blisters. In transitioning to the latent stage, these viruses enter the sensory nerves and spinal ganglia, where they persist throughout the lifetime of the patient. They are often reactivated, causing a recurrence of symptoms.

It is always recommended to determine a woman’s HSV status during pregnancy to estimate the newborn’s risk for perinatal infection.

Detection of IgM antibodies against HSV virus is important to confirm an acute primary infection, which has been detected via PCR. Besides, IgM antibodies may also be detectable in cases of recurrent or persistent infection.

IgG antibodies against the type-specific glycoprotein G1 are formed two to three months after a primary infection with the type 1 herpes simplex virus. IgG-class antibodies against glycoprotein G2 are detectable several weeks after primary infection.

Anti-HSV-2 IgG (Cat. no. ORG 904G)

Anti-HSV-2 IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against herpes simplex virus type 2 (HSV-2) in human serum or plasma.

Anti-HSV-2 IgM Abs. (Cat. no. ORG 904MX)

Anti-HSV-2 IgM with rheumatoid factor absorbent is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against herpes simplex virus type 2 (HSV-2) in human serum or plasma.

IgM-class rheumatoid factor antibodies can distort the results of pathogen-specific IgM antibody tests. The Anti-HSV-1 IgM Abs. test is equipped with the ORGENTEC rheumatoid factor absorbent. This reagent absorbs any rheumatoid factors that may be present during sample processing in the Alegria instrument, making separate preparation of the serum sample unnecessary.

Format: Alegria® Monotest strips for the fully automated Alegria® / Alegria® 2 analyzers.

Specifications

Also available as Alegria Monotest (ORG 905G, ORG 905MX).

Documents

• Instruction for Use – ORG 904G
• Safety Data Sheet – ORG 904G
• Instruction for Use – ORG 904MX
• Safety Data Sheet – ORG 904MX

Instruction for Use Revision 8. Earlier versions and additional languages can be found in the document archive.

Ordering Information