Oleoylethanolamide, GPR119 agonist; stimulates lipolysis

Product Details

Formal Name: N-(2-Hydroxyethyl)-9Z-octadecenamide

Alternate Names: OEA; Oleylethanolamide

Molecular Formula: C₂₀H₃₉NO₂

Formula Weight: 325.53

CAS Number: 111-58-0

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

GPR119 agonist; stimulates lipolysis

Functions

Endogenous anandamide-like lipid acting as a PPARα agonist but does not bind to cannabinoid receptors. Biosynthesis via the action of NAPE-PLD on N-acylphosphatidylethanolamine. Agonist at GPR119 and has been suggested to be its endogenous ligand. Inhibits food intake in rodents. Extends the lifespan of C. elegans.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Research use only.

Documents

• Datasheet (PDF)