NNGH, MMP inhibitor (pan-specific)

Product Details

Formal Name: N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid

Molecular Formula: C₁₃H₂₀N₂O₅S

Formula Weight: 316.38

CAS Number: 161314-17-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 8 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

MMP inhibitor (pan-specific)

Functions

Potent pan-specific inhibitor of matrix metalloproteinases ( MMP3 Ki=0.013 µM). Inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced  thermal hyperalgesia. Cell Permeable.

Application Procedures

First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 8 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)