Product Details
Formal Name: 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Alternate Names: AMN-107
Molecular Formula: C28H22F3N7O
Formula Weight: 529.52
CAS Number: 641571-10-0
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 50 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
BCR-ABL inhibitor
Functions
A novel, selective BCR-ABL inhibitor. More potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM). Induces apoptosis.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Research use only.
Documents
