Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Sphingosine kinase inhibitor
Functions
Synthetic derivative of D-erythro-sphingosine (synthetic). Endogenous sphingolipid. Inhibits sphingosine kinase (IC50 = 5µM). Induces apoptosis in a variety of cell lines.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
