MidGee hoop ultrafiltration hollow fiber cartridges

Tangential flow ultrafiltration hoop cartridges with polysulfone membrane that allow easy scaling even with small product volumes.

• Rapid concentration and/or diafiltration of critical biological solutions.
• Full range of UF pore sizes and lumen diameters.
• 60 cm and 110 cm path lengths match pilot- and production-scale designs.
• Autoclavable and are compatible with aqueous solutions and most alcohols.
• High product recoveries with minimal shear denaturation.
• No wall effects to distort scale-up projections as with plate and frame devices.

Scale up or down easily

Throughout the R&D process, access to product is often limited. As a result, investigations into optimization of operating conditions are sometimes postponed or avoided entirely. Now scale-up and scale-down using minimum product volumes is easy with our MidGee Hoop hollow fiber cartridges.

Hoop cartridges provide all the critical features of full production scale in a miniature tangential flow device, allowing simulation of process parameters, including path length, with minimal solution volume and pump capacity.

The uniform flow path design from laboratory- to production-scale makes hollow fibers the most attractive of the various tangential flow configurations for linear scale-up.

Small is beautiful

MidGee Hoop cartridges are optimized for use in our compact MidJet Tangential Flow Filtration System, which includes

• A miniature peristaltic pump with exchangeable saddles to accommodate size 14 and 16 tubing
• Reservoirs for retentate, diafiltrate and permeate
• Precision backpressure control valve
• A convenient platform for mounting the cartridge and pump with recesses to accommodate three reservoirs

Documents

• Data file (PDF)
• Instructions for use (PDF)