Metyrapone, Cytochrome P450 inhibitor

Product Details

Formal Name: 2-Methyl-1,2-dipyridin-3-yl-propan-1-one

Molecular Formula: C₁₄H₁₄N₂O

Formula Weight: 226.27

CAS Number: 54-36-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Cytochrome P450 inhibitor

Functions

Inhibits cytochrome P450-mediated prostaglandin omega hydroxylation. Inhibits steroid 11β-hydroxylase thereby inhibiting cortisol biosynthesis.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Research use only.

Documents

• Datasheet (PDF)