Methoprene acid (53092-52-7) is an analog of insect juvenile hormone which acts as an insect growth regulator. Binds directly and selectively to the retinoid X receptor (RXR) acting as a transcriptional activator in both insect and mammalian cells with no activity at RAR. Negatively regulates thrombosis and hemostasis. Induces neurosteroid biosynthesis in human glial GI-1 cells. Increases the expression of the brown-fat-uncoupling-protein-1 gene (ucp-1).
Application Procedures
First dissolved in DMSO or Ethanol, then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
