ME-0328, PARP3 inhibitor

Product Details

Formal Name: 3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide

Molecular Formula: C₁₉H₁₉N₃O₂

Formula Weight: 321.38

CAS Number: 1445251-22-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming).

Storage: RT

Stability: ≥ 1 year.

Applications

PARP3 inhibitor

Functions

A potent and selective PARP3 inhibitor (IC50=0.89 μM). Selective over PARP-1, PARP-2 and other ARDT enzymes (IC50=6.3, 10.8 and >30 μM respectively)

Application Procedures

First dissolved in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)