Mdivi, Mitochondrial division inhibitor

Product Details

Formal Name: 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone

Alternate Names: Mdivi-1

Molecular Formula: C₁₅H₁₀Cl₂N₂O₂S

Formula Weight: 353.23

CAS Number: 338967-87-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Mitochondrial division inhibitor

Functions

Selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)