Maestro Edge MEA System

Software

The Maestro Edge platform is available with six software modules: Neural, Cardiac, MEA Viability, MEA Automation, Impedance, and GxP Impedance. Select the software modules to match your assay needs:

Neural – Measure the key parameters of neural network function, including activity (are the neurons functional?), synchrony (are the synapses functional?), and oscillation (is the network functional?).

Cardiac – Record the four key measures of functional cardiac performance, label free and in real time in every well of the multiwell plate: action potential (a.k.a. LEAP assay); field potential; propagation; and contractility.

MEA Viability – Measure cell viability and coverage on MEA plates for a complete structure-function assay.

MEA Automation – Automate Cardiac and Neural MEA assays with this API for interfacing with liquid handling platforms.

Impedance – Track cell proliferation, morphology, and viability label-free and in real-time. Ideal for immuno-oncology, cytotoxicity, virology, cell migration, cell proliferation, GPCR assays, and many more.

GxP Impedance – Achieve FDA 21 CFR Part 11 compliance in GMP/GLP labs with this version of the Impedance Software Module.

Consumables

The Maestro Edge system is compatible with the 24- and 6-well versions of Axion’s MEA plates, and the 96-well impedance assay plate. Select the multiwell plates to match your assay needs:

CytoView MEA™ – The premium Maestro multiwell MEA plate with a transparent well bottom for cell visualization and assay multiplexing. The 24-, and 6-well plate formats are compatible with the Maestro Edge.

BioCircuit MEA™ – Maestro MEA plates with an opaque well bottom delivering high-quality results at the lowest cost per well. The 24-well plate format is compatible with the Maestro Edge.

Lumos MEA™ – Maestro MEA plates designed for use with the Lumos system, featuring a transparent well bottom and light-focusing lid. The 24-well plate format is compatible with the Maestro Edge.

CytoView-Z™ – The Maestro impedance plate with a transparent well bottom for cell visualization and assay multiplexing. Available in a 96-well plate format.

Peripherals

Lumos™ is a multiwell light stimulation system for optogenetic assays, that pairs with the Maestro Pro. The Maestro Pro platform is compatible with all three formats of the Lumos optical stimulation system. Select the Lumos system to match your assay needs:

Lumos 96™ – For use with Lumos MEA 96 plates. The Lumos 96 system has two LEDs per well (green and blue).

Lumos 48™ – For use with Lumos MEA 48 plates. The Lumos 48 system has four LEDs per well (red, orange, green and blue).

Lumos 24™ – For use with Lumos MEA 24 plates. The Lumos 24 system has four LEDs per well (red, orange, green and blue).

MEA Creator Kit – Connect user-made MEAs to Maestro MEA systems. Test your electrode designs, layouts, and integrate additional components with an easy-to-use adapter plate.

Cross-compatible Platforms

The Maestro Edge system has cross-compatibility with:

Omni™ – See whole-plate images of your cultures next to real-time activity measurements. Confirm electrode coverage and culture health with just a few clicks from AxIS Navigator. Compatible with the Omni system.