Solubility: Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
Storage: -20°C
Stability: ≥ 1 year.
Applications
Nuclear export inhibitor
Functions
Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.
Application Procedures
Solutions in DMSO are unstable and must be used within one working day. Do not store DMSO solutions.
