Solubility: Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 14 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Induces chondrocyte differentiation
Functions
Promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Displays chrondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 60 mg/ml) or in Ethanol (up to 14 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
