INK-128, mTOR inhibitor
Vendor: TriBioScience
SKU: TBI3362-5MG
In stock
Product Details
Formal Name: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Alternate Names: MLN-0128
Molecular Formula: C15H15N7O
Formula Weight: 309.33
CAS Number: 1224844-38-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
mTOR inhibitor
Functions
A potent and selective, ATP-competitive inhibitor of mTOR kinase, Ki = 1.4 nM. Inhibits growth and proliferation of various breast cancer cell lines and human endothelial cells.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Research use only.
Documents
Specifications
- Alternate names MLN-0128
- Cas number 1224844-38-5
- Formal name 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Formulation powder
- Formula weight 309.33
- Molecular formula C15H15N7O
- Purity >98%
- Solubility Soluble in DMSO (up to 25 mg/ml)
- Stability ≥ 1 year
- Storage -20°C
links and documants
- Datasheet url Click here
- Msds url Click here
- Source url Click here
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INK-128, mTOR inhibitor
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