ICG-001, Wnt/β-catenin inhibitor

Product Details

Formal Name: (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

Molecular Formula: C₃₃H₃₂N₄O₄

Formula Weight: 548.63

CAS Number: 847591-62-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Wnt/β-catenin inhibitor

Functions

Inhibits TCF/β-catenin mediated transcription by specifically blocking β-catenin/CBP interaction.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)