Tribioscience’s HAT Supplement Solution is a liquid mixture of hypoxanthine, aminopterin, thymidine (HAT) for hybridoma cell selection. It is used for the preparation of selection medium for hybridoma. The myeloma cell is deficient in the enzyme hypoxanthine-guanine phosphoribosyl transferase (HGPRT) or thymidine kinase (TK) and cannot survive in HAT selection medium. This selection Solution has been verified for use in hybridoma development and monoclonal antibody production.
Main Components
This product is a chemically defined liquid medium. The main components are as below:
Hypoxanthine (H)
Aminopterin (A)
Thymidine (T)
Storage Condition
Shelf Life: Store at -20°C for 1 year.
Applications
Used for Hybridoma cell selection for monoclonal antibody production.
